LTP in Synapse
Author:
Dilawar Singh
Last Updated:
há 6 anos
License:
Creative Commons CC BY 4.0
Abstract:
Long Term Potentiation (LTP) in synapse.
\begin
Discover why over 20 million people worldwide trust Overleaf with their work.
Long Term Potentiation (LTP) in synapse.
\begin
Discover why over 20 million people worldwide trust Overleaf with their work.
% FIGURE shows LTP in spine.
\RequirePackage{luatex85,shellesc}
\documentclass[crop]{standalone}
\usepackage{pgfplots}
\pgfplotsset{compat=1.15}
\usepackage{tikz}
\usetikzlibrary{positioning,calc,shapes,hobby}
\usetikzlibrary{scopes}
\usetikzlibrary{fit}
\usetikzlibrary{intersections, pgfplots.fillbetween}
\usetikzlibrary{arrows}
% Background layer.
\pgfdeclarelayer{bg}
\pgfdeclarelayer{ft}
\pgfsetlayers{bg,main,ft}
\renewcommand{\familydefault}{\sfdefault}
\pgfmathsetseed{10}
\input{structure}
\input{channel}
% Macros
\newcommand\VESICLE[3]{ % name, location, scale
\def\NODESIZE{1}
\begin{scope}[shift={(#2)}]
\node[circle,fill=white, inner sep=#3*\NODESIZE mm] (#1) at (0,0) {};
\foreach \i in {1,...,5} {
\pgfmathsetmacro\x{rand*\NODESIZE}
\pgfmathsetmacro\y{rand*\NODESIZE}
\node[fill=black!50, draw=none,circle,inner sep=0.7pt] at (\x mm,\y mm) {};
}
\end{scope}
}
\begin{document}
\begin{tikzpicture}[hobby]
\SPINEWITHAXON{S1}{(-4,0)}{0.7}
\SPINEWITHAXON{S2}{(4,0)}{1.2}
% Now add some pre-synaptic vesicle
\VESICLE{v1}{[yshift=0.75mm]S1_PRE_R2}{1}
\VESICLE{v2}{[shift=(10:7mm)]v1}{1.2}
\VESICLE{v3}{[shift=(180:4mm)]v1}{1}
\VESICLE{v1}{[yshift=0.75mm]S2_PRE_R2}{1.2}
\VESICLE{v2}{[shift=(20:7mm)]v1}{1.2}
\VESICLE{v3}{[shift=(170:6mm)]v1}{1.2}
\draw[-stealth, black, line width=1mm] (S1) to[] node[above] {\Large LTP} (S2);
\draw[-stealth, gray, dashed, very thick] ([yshift=-4mm]S2.west) to[]
([yshift=-4mm]S1.east);
% ADD RECEPTORS ON POST MEMBRANE.
\CHANNEL{S1_SN1}{0.2}{0.1}{0}{black}{10}
\CHANNEL{S1_SN2}{0.3}{0.2}{40}{blue}{0}
\CHANNEL{S1_SN3}{0.2}{0.1}{30}{black}{-30}
\CHANNEL{S1_SE1}{0.2}{0.1}{0}{black}{-60}
\CHANNEL{S2_SN1}{0.2}{0.1}{0}{black}{10}
\CHANNEL{S2_SN2}{0.3}{0.2}{40}{blue}{0}
\CHANNEL{S2_SN3}{0.2}{0.1}{30}{black}{-30}
\CHANNEL{S2_SE1}{0.2}{0.1}{0}{black}{-60}
\coordinate (x1) at ([shift=(110:4mm)]S2_SE1);
\coordinate (x2) at ([shift=(20:4mm)]S2_SN1);
\coordinate (x3) at ([shift=(0:4mm)]S2_SN2);
\CHANNEL{x1}{0.3}{0.2}{40}{blue}{-60}
\CHANNEL{x2}{0.3}{0.2}{40}{blue}{10}
\CHANNEL{x3}{0.2}{0.1}{0}{black}{-10}
\end{tikzpicture}
\end{document}